A plausible biological mechanism is not well elucidated when study suggests long-term use of certain reflux medications is associated with a higher risk of dementia. No proof of causality and is confounded by other life factors August 17, 2023September 14, 2023Dr. Barry Dworkin Medical Mythbusting Commentary for August 17, 2023 [display_podcast] Source:Long-term use of certain reflux medications is associated with a higher risk of dementia, study suggests Reference:Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Related posts: Lack of evidence has not stopped increased use of antipsychotic meds to calm agitated elderly There is no evidence from this study to suggest that antidepressants can triple the risk of people developing dementia. Two stories that underlie importance of risk and benefit of using medications Opiate crisis in Ontario leads to medication updates and increases in support services dementiaPPI