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Work on HIV vaccine continue apace with encouraging in vitro results. Now need to find out how well it works in human clinical studies.
Medical Mythbusting Commentary for March 27, 2024 Source:‘Another step closer’: Western University researchers work on cure for AIDS
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Third-ever person declared cured of HIV following stem cell treatment
Medical Mythbusting Commentary for February 24, 2023 Source:3rd-ever person declared cured of HIV following stem cell treatment Reference:In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation
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Study in Nature outlines how in vitro and in vivo (mouse model), specific white blood cells (B-Cells) can be genetically programmed to produce anti-HIV antibodies thus offer a one-time treatment for the disease. Long way to go but elegant study design.
Medical Mythbusting Commentary for June 15, 2022 Source:A “One-Time” Treatment for HIV Could Be on the Horizon Reference:In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice
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HIV vaccine hopes should not be “dashed” by trial failure. Results contribute to understanding and formulating new approaches. We learn from our mistakes and failures in order to attain our goals.
Medical Mythbusting Commentary for February 5, 2020 Source:HIV vaccine hopes dashed by trial results
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New therapeutic approach to treat HIV offers hope for eradication of virus in the body. Still many hurdles to go.
Health Headlines Commentary for October 4, 2016 Source: HIV cure possible after disease becomes undetectable in blood of British man
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HIV deleted from infected cells and they revert to normal function
Madely Health Headlines Commentary for March 26, 2015 Source: Scientists ‘delete’ HIV virus from human DNA for the first time Reference: RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
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High dose treatment of HIV in newborns seems to confer a functional cure in reported instances.
Madely Health Headlines Commentary for March 12, 2014 Source: Children’s hospitals study newborns’ ability to fight off HIV
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Gene therapy helps retrain immune system to attack HIV
Madely Health Headlines Commentary for March 7, 2014 Source: Immune upgrade gives ‘HIV shielding’ Reference: Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
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New insight into how HIV destroys the immune system leads to drug that partially blocks the process: more clinical studies required
Madely Health Headlines Commentary for December 23, 2013 [display_podcast] Source: New AIDS treatment? Experimental drug blocks HIV from killing immune system cells in lab test Reference: Gilad Doitsh, Nicole L. K. Galloway, Xin Geng, Zhiyuan Yang, Kathryn M. Monroe, Orlando Zepeda, Peter W. Hunt, Hiroyu Hatano, Stefanie Sowinski, Isa Muñoz-Arias, Warner C. Greene. Cell death by…