Researchers have found a genetic mutation for hypothyroidism that applies to 1/5000 people and that can lead to increased weight gain. Claims that it is a genetic link to obesity requires some jumping of the hoops.

Medical Mythbusting Commentary for June 25, 2024

Source:
Researchers have found a ‘clear genetic trigger for obesity’ that applies to some people

Reference:

SMIM1 absence is associated with reduced energy expenditure and excess weight