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Targeted gene-altering therapy reduced LDL-cholesterol levels by 50 per cent in patients with severely elevated cholesterol levels.
Medical Mythbusting Commentary for September 2, 2026 Source:With the snip of a gene, scientists hope to erase high cholesterol for life Reference:Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3
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Newer understanding of new blood vessel growth after heart attack may lead to treatments to promote better bypass circulation.
Medical Mythbusting Commentary for August 24, 2026 Source:Your Heart Can Actually Build Its Own Bypass After a Heart Attack Reference:Tracing the origins of de novo coronary collateral formation in cardiac repair
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Study in Nature Communications reports that dietary feeding of phosphatidylcholine or its precursor choline restored more youthful mitochondrial structure and function in worm and human cell culture models restoring more youthful function.
Medical Mythbusting Commentary for August 18, 2026 Source:Scientists Uncovered a Hidden Switch Inside Our Cells That Could Slow—or Even Reverse—Aging Reference:Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging
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Scientists decipher how T cells sense enemies—such as cancer—at point of contact
Medical Mythbusting Commentary for July 29, 2026 Source:Scientists decipher how T cells sense enemies—such as cancer—at point of contact Reference:PD-1 signaling and PD-1 blockade–mediated tumor control are established at microvillar T cell contacts
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The mechanism of why statin medications can cause muscles aches has been outlined but this pathway is found in a minority of patients so other reasons remain elusive.
Medical Mythbusting Commentary for June 3, 2026 Source:A Painful Side Effect of Statins Explained After Decades of Mystery Reference:Structural basis for simvastatin-induced skeletal muscle weakness associated with type 1 ryanodine receptor T4709M mutation
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Remnant cholesterol levels found to be an independent risk factor for heart disease. We discuss what this is and what the approach to management entails.
Medical Mythbusting Commentary for May 26, 2026 Source:Experts have found a new type of cholesterol. And it could be the most dangerous Reference: Source: openevidence.comRemnant cholesterol — defined as total cholesterol minus LDL-C minus HDL-C — is an emerging and increasingly recognized causal risk factor for ASCVD. Management centers on lifestyle modification as first-line therapy,…
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Metformin shown to increase a biological effect of exercise in men with prostate cancer reducing insulin resistance, easing metabolic stress and weight gain. What this isn’t is exercise in a pill.
Medical Mythbusting Commentary for April 14, 2026 Source:Exercise in a Pill? Metformin Shows Surprising Effects in Cancer Patients Reference:The anti-obesogenic metabolite, Lac-Phe, is elevated by metformin treatment in prostate cancer patients
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A common oral bacterium may contribute to stimulating existing breast cancer shown in mouse model study
Medical Mythbusting Commentary for February 2, 2026 Source:This Common Bacterium Hiding in Your Mouth May Help Trigger Breast Cancer Reference:A pro-carcinogenic oral microbe internalized by breast cancer cells promotes mammary tumorigenesis
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Intestinal bacterial replacement pills show safety and reduced the side effects from chemotherapy agents used to treat advanced kidney cancer in Phase 1 study
Medical Mythbusting Commentary for January 29, 2026 Source:‘Poop pills’ developed in London show promise for cancer patients in early trial