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Tweaking CAR-T activity with on/off switches may reduce cytokine release syndrome.
Medical Mythbusting Commentary for September 12, 2022 Source:Immune cells engineered to battle cancer can be turned ‘on’ or ‘off’ Reference:High-performance multiplex drug-gated CAR circuits
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Case studies reported in Nature of decade-long leukaemia remissions after CAR T treatment. #GoScience
Medical Mythbusting Commentary for February 7, 2022 Source:Cancer patients called cured a decade after gene therapy Reference:Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
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CAR-T therapy has its successes for treating leukemias and other blood cancers but please do not sell it in press releases with testimonials that do not cite the serious side effects of treatment.
Medical Mythbusting Commentary for February 3, 2020 Source:CAR-T cell therapy—new hope when standard cancer treatments fail
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Ontario Ministry of Health rejects family’s application for Phase 1 trial of donor-derived Car T-cell treatment in the U.S. for their 17-year-old son.
Medical Mythbusting Commentary for December 17, 2019 Source:‘This might be our last Christmas together’: family rejected by Ontario government after requesting cancer treatment in United States