November 4, 2021 Clinical Research AstraZeneca applies for approval of antibody treatment that provides passive immunity against COVID-19 for up to a year according to the press release. Indicated for vulnerable people who are immunocompromised or who have not responded to the vaccine.
June 30, 2021 General information Health Canada adds Capillary Leak Syndrome, as an extremely rare side effect of AZ and Covishield vaccine. Six people in Europe and UK reported had syndrome after vaccine out of 78 million doses given. One case in Canada reported to date. #FullDisclosure
June 15, 2021 Health Statistics Observational studies show excellent efficacy of two-dose regimen of Pfizer or AZ against the Delta variant dramatically reducing the risk of hospitalization. #vaccineswork
June 14, 2021 Allergy/Immunology What should your #seconddose of #covidvaccine be if 1st was AZ? Factors include wait-time/availability, Delta variant prevalence, occupational risks, and study evidence. Answer seems to leaning to Pfizer or Moderna as 2nd dose of choice.
June 2, 2021 Health Policy NACI recommends second dose Pfizer/moderna vaccine for those who had AZ as their first dose.
May 31, 2021 Health Policy With all that has happened with miscommunication and damage to confidence, if you want to make people suspicious of your decision Health Canada, this is the way to do it.
May 27, 2021 Allergy/Immunology German study proposes a mechanism behind the rare blood clots associated with AstraZeneca vaccine.
May 19, 2021 Clinical Research For those who have had AstraZeneca as their first dose, small Spanish study shows that using Pfizer as the second dose is safe and effective. More evaluation and other trials are ongoing but still, good news.
May 13, 2021 Clinical Research Short-lived common side effects including fever, chills, pain, and headache after mixing AZ with Pfizer vaccine reported in @TheLancet. Immunogenicity results to be reported in June and if mixing is a viable option (likely but assumption needs evidence).