We have seen numerous studies in basic science research produce results that surprise the investigator and open up new insights into the pathophysiology or mechanism of disease. A study published in the July 13, 2006 online issue of the Journal of Clinical Investigation found that a protein previously linked to the development of type 2 diabetes and atherosclerosis may also be associated with asthma.

• Gökhan Hotamisligil, James Stevens Simmons Professor of Genetics and Metabolism and Chair of the Department of Genetics and Complex Diseases at the Harvard School of Public Health.