Dr. Barry Dworkin

For those who have had AstraZeneca as their first dose, small Spanish study shows that using Pfizer as the second dose is safe and effective. More evaluation and other trials are ongoing but still, good news.

Medical Mythbusting Commentary for May 19, 2021

Source:
Spanish Study Finds AstraZeneca Vaccine Followed by Pfizer Dose Is Safe and Effective

Related posts:

  1. Will Covid vaccine mixing be adopted as health policy? They use different delivery systems carrying the genetic instruction set to produce the same spike protein, ergo ongoing studies are evaluating clinical outcomes to determine if assumption is true.
  2. In vitro studies reported in NEJM show that Pfizer/Moderna vaccines were still able to neutralize variant B.1.351 from South Africa despite reduction in neutralizing antibodies. Authors’ opinion is that vaccine remains efficacious. More to follow.
  3. Short-lived common side effects including fever, chills, pain, and headache after mixing AZ with Pfizer vaccine reported in @TheLancet. Immunogenicity results to be reported in June and if mixing is a viable option (likely but assumption needs evidence).
  4. What should your #seconddose of #covidvaccine be if 1st was AZ? Factors include wait-time/availability, Delta variant prevalence, occupational risks, and study evidence. Answer seems to leaning to Pfizer or Moderna as 2nd dose of choice.