Researchers at The Hospital for Sick Children (SickKids), the University of Calgary and The Jackson Laboratory, Bar Harbor, Maine have found a new mechanism that is directly involved in the pathophysiology of diabetes. This new insight into the mechanism of diabetes has advanced possible new treatment strategies, with the potential as seen in animal trials of achieving reversal of the disease without severe, toxic immunosuppression. This research is reported in the December 15 issue of the journal Cell.

• Dr. Hans-Michael Dosch, MD, PhD, Senior Scientist (Neurosciences and Mental Health) at Sick Kids in Toronto and Professor in the Depts. of Immunology & Paediatrics at University of Toronto.