Original broadcast date: March 9, 2008

With a greater understanding behind the mechanism or pathophysiology of disease, the ability to provide effective treatments can follow. An international consortium of scientists led by Oklahoma Medical Research Foundation investigator John B. Harley, M.D., Ph.D., has identified multiple genes linked to lupus, a devastating autoimmune disease that affects as many as 15 million people worldwide. The group’s findings appear online in two related articles in the Feb. edition of the journal Nature Genetics.

• Dr. John Harley, M.D., Ph.D., Chair, Arthritis and Immunology Research Program, Chair & Professor of Immunology, Medicine and Research Professor at the University of Oklahoma Health Sciences Center, Staff Physician, U.S. Department of Veterans Affairs Medical Center, Oklahoma
  City and lead author of this report