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Phase 1 targeted gene editing study demonstrates safety and reduction in LDL cholesterol levels through specific protein pathway
Medical Mythbusting Commentary for August 17, 2026 Source:‘An extremely exciting milestone!’: landmark treatment slashes cholesterol by 62% with a single dose Reference:In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia
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Irritable Male Syndrome (IMS) Is Not An Actual Condition
Medical Mythbusting Commentary for April 7, 2026 Source:Irritable Male Syndrome (IMS) Is An Actual Condition — And It Could Explain A Lot Irritable Male Syndrome (IMS) is not a true, distinct medical condition in humans. The HuffPost article accurately summarizes symptoms (irritability, fatigue, low libido, mood changes) linked to gradual testosterone decline after age 40, citing…
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Millions of Women Take This Daily Medication. It’s Now ‘Confirmed’ to Increase Breast Cancer Risk by about 1/7500 women per year and fails to mention the 20-40% risk reduction for uterine and ovarian cancer when used for years.
Medical Mythbusting Commentary for November 27, 2025 Source:Millions of Women Take This Daily Medication. It’s Now ‘Confirmed’ to Increase Breast Cancer Risk
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F.D.A. decision to the Black Box warnings for long-term HRT use is not supported by the available evidence. There is a definite use for treating menopausal symptoms but there are better medications to prevent heart disease and osteoporosis.
Medical Mythbusting Commentary for November 12, 2025 Source:F.D.A. Will Remove Black Box Warnings From Hormone Treatments for Menopause
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There are likely multiple reasons for men to have irritability, depression and diminished strength as they age. I am not convinced that it all falls under the moniker of Irritable Male Syndrome.
Medical Mythbusting Commentary for September 25, 2025 Source:Irritable Male Syndrome (IMS) Is An Actual Condition — And It Could Explain A Lot
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There are likely many factors that contribute to early puberty. Study suggests that a history of breastfeeding could prevent some children from developing it.
Medical Mythbusting Commentary for August 20, 2025 Source:Breastfeeding could help prevent early puberty in girls and boys, South Korean study finds Reference:Breastfeeding, Prepubertal Adiposity, and Development of Precocious Puberty
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GLP-1 receptor agonists like semaglutide (Ozempic) may help increase testosterone levels in men but whether that is clinically relevant remains to be determined.
Medical Mythbusting Commentary for August 18, 2025 Source:Weight loss drugs can boost testosterone in men, study finds
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A preprint, non-peer-reviewed study states that weight-loss drugs such as Wegovy are more likely to cause temporary hair loss compared to Contrave. The latter is not overly efficacious hence less weight loss therefore less hair loss.
Medical Mythbusting Commentary for March 18, 2025 Source:Weight-Loss Drugs Like Wegovy Are Linked to Hair Loss Reference:Risk of Hair Loss with Semaglutide for Weight Loss